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Angiostrongylus costaricensis

BioProject PRJEB494 | Data Source Wellcome Sanger Institute | Taxonomy ID 334426

About Angiostrongylus costaricensis

The nematode Angiostrongylus costaricensis is the causal agent of abdominal, or intestinal, angiostrongyliasis. Humans are incidental hosts that become infected through ingestion of raw or undercooked infected rats (definitive host) snails, slugs, crabs, freshwater shrimps, or vegetables contaminated by slime from or parts of infected snails and slugs.

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Antonio Osuna (Universidad de Granada) as part of the 50 Helminth Genomes project. The assembly uses Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction.

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes project. An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Key Publications

Assembly Statistics

AssemblyA_costaricensis_Costa_Rica_0011_upd, GCA_900624975.1
StrainCosta Rica
Database VersionWBPS19
Genome Size262,782,696
Data SourceWellcome Sanger Institute
Annotation Version2014-06-50HGPpatch

Gene counts

Coding genes13,417
Gene transcripts13,417

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