About Loa loa
The nematode Loa loa, or eye worm, is the filarial species that causes Loa loa filariasis. L. loa is one of three parasitic filarial nematodes that cause human subcutaneous filariasis in Africa and India. Maturing larvae and adults of the "eye worm" occupy the subcutaneous layer of the skin the fat layer of humans, causing disease.
There is 1 alternative genome project for Loa loa available in WormBase ParaSite: PRJNA246086
Genome assembly: Loa_loa_V3
The L. loa genome was sequenced by the Filarial Worms sequencing project at BROAD institute, as described by Desjardins et al (2013).
The gene predictions were made by the Filarial Worms sequencing project at BROAD institute, as described by Desjardins et al (2013). The version represented here is consistent with the INSDC records.
What can I find? Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs.
What can I find? Orthologues, paralogues, and gene trees across multiple species.
- Desjardins CA, Cerqueira GC, Goldberg JM, Dunning Hotopp JC, Haas BJ, Zucker J, Ribeiro JM, Saif S, Levin JZ, Fan L, Zeng Q, Russ C, Wortman JR, Fink DL, Birren BW, Nutman TB. Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. Nat Genet, 2013;45(5):495-500
|Strain||L. loa Cameroon isolate|
|Data Source||Broad Institute|