WormBase ParaSite HomeVersion: WBPS9 (WS258)

Thelazia callipaeda

BioProject PRJEB1205 | Data Source Wellcome Trust Sanger Institute | Taxonomy ID 103827

About Thelazia callipaeda

The nematode Thelazia callipaeda, or eyeworm, is a parasite of most mammals (including humans, dogs and cats). It is the most common cause of thelaziasis, symptoms of the eye infestation include conjunctivitis, excessive watering (lacrimation), visual impairment, and ulcers or scarring of the cornea.

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Manuela Schnyder (University of Zurich), using Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction (Helminth Genomes Consortium, unpublished).

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes Initiative (Helminth Genomes Consortium, unpublished). An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Assembly Statistics

AssemblyT_callipaeda_Ticino_v1_0_4, GCA_000981425.1
StrainSwitzerland/Ticino
Database VersionWBPS9
Genome Size75,392,092
Data SourceWellcome Trust Sanger Institute
Annotation Version2014-06-50HGPpatch

Gene counts

Coding genes10,912
Gene transcripts10,912

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About this species