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Heligmosomoides polygyrus

Taxonomy ID 6339

The nematode Heligmosomoides polygyrus (formerly known as Nematospiroides dubius) is a common parasite found in the duodenum and small intestine of woodmice and other rodents. The laboratory strain that has been sequenced was originally isolated from Peromyscus in California (Behnke and Harris, 2010); natural parasites from European wood mice (Apodemus sp.) are somewhat distinct, giving rise to some debate about the correct name and taxonomy of this species (Cable et al, 2006; Behnke and Harris, 2010; Maizels et al, 2010), with suggestions that the laboratory strain is named H. polygyrus bakeri or H. bakeri, and the European strain H. polygyrus polygyrus. The laboratory strain has been maintained as described by Camberis et al (2003) and is often used to model human helminth infection as it can establish chronic infection in different strains of mice.

Genome Projects

There are 2 genome projects for Heligmosomoides polygyrus:

  • PRJEB1203: Wellcome Trust Sanger Institute (Strain Scotland/Edinburgh)
  • PRJEB15396: University of Edinburgh

About this species