WormBase ParaSite HomeVersion: WBPS9 (WS258)

Onchocerca volvulus

BioProject PRJEB513 | Data Source WormBase | Taxonomy ID 6282

About Onchocerca volvulus

The nematode Onchocerca volvulus is a gonochoristic filarial parasite of humans causing Onchocerciasis. Onchocerciasis, or River Blindness, is a neglected tropical disease (NTD) which affects over 37 million people, mainly in Africa. It is a severely debilitating disease, which is transmitted to humans by the bite of Simulium blackflies that live and breed near fast-flowing streams and rivers.

Genome Assembly & Annotation

Assembly

The reference genome for Onchocerca volvulus has been produced by the Parasite Genomics group at the Wellcome Trust Sanger Institute, in collaboration with Sara Lustigman (New York Blood Center). A combination of deep sequencing and optical mapping was used on material from a single adult worm from the Republic of Cameroon.

Annotation

The gene models are actively curated by WormBase.

Key Publications

  • Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S. The genome of Onchocerca volvulus, agent of river blindness. Nat Microbiol, 2016;2():16216

Assembly Statistics

AssemblyO_volvulus_Cameroon_v3, GCA_000499405.1
StrainO. volvulus Cameroon isolate
Database VersionWBPS9
Genome Size96,427,779
Data SourceWormBase
Annotation VersionWS254

Gene counts

Coding genes12,117
Non coding genes408
Small non coding genes408
Pseudogenes39
Gene transcripts15,088

Learn more about this widget in our help section

This widget has been derived from the assembly-stats code developed by the Lepbase project at the University of Edinburgh

About this species