WormBase ParaSite HomeVersion: WBPS9 (WS258)

Wuchereria bancrofti

BioProject PRJEB536 | Data Source Wellcome Trust Sanger Institute | Taxonomy ID 6293

About Wuchereria bancrofti

The nematode Wuchereria bancrofti is a human parasite that is the major cause of lymphatic filariasis. It is the most prevalent human infective filarial worm, affecting over 120 million people, primarily in Central Africa and the Nile delta, South and Central America, and the tropical regions of Asia. If the infection is left untreated, it can develop into elephantiasis.

There is 1 alternative genome project for Wuchereria bancrofti available in WormBase ParaSite: PRJNA275548

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Rick Maizels (Edinburgh University), using Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction (Helminth Genomes Consortium, unpublished).

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes Initiative (Helminth Genomes Consortium, unpublished). An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Assembly Statistics

AssemblyW_bancrofti_Jakarta_v2_0_4, GCA_000951595.1
Database VersionWBPS9
Genome Size76,991,470
Data SourceWellcome Trust Sanger Institute
Annotation Version2014-06-50HGPpatch

Gene counts

Coding genes13,058
Gene transcripts13,058

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About this species