About Echinococcus multilocularis
The cestode Echinococcus multilocularis is a member of the Cyclophyllidea, which comprise the majority of tapeworms that are of medical importance. The disease alveolar echinococcosis, which is caused by the larval stage of E. multilocularis, is considered to be one of the most dangerous worm infections in the world. E. multilocularis has recently spread in Europe, Japan, and North America to areas that were previously free of the parasite leading to the classification of alveolar echinococcosis as an emerging zoonosis.
Genome Assembly & Annotation
The E. multilocularis reference genome was sequenced by the Parasite Genomics group at the Wellcome Trust Sanger Institute in collaboration with Klaus Brehm (University of Würzburg). The initial version of the genome was described in Tsai et al (2013). The assembly has subsequently been improved, and the version represented here since ParaSite release 5 (January 2016) is NCBI EMULTI002 .
The original gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute as described by Tsai et al (2013). The gene models have since been subject to iterative improvement, and version represented since ParaSite version 5 (January 2016) here is the November 2015 snapshot.
- Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, Sánchez-Flores A, Brooks KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM, Cai X, Camicia F, Clark R, Cucher M, De Silva N, Day TA, Deplazes P, Estrada K, Fernández C, Holland PWH, Hou J, Hu S, Huckvale T, Hung SS, Kamenetzky L, Keane JA, Kiss F, Koziol U, Lambert O, Liu K, Luo X, Luo Y, Macchiaroli N, Nichol S, Paps J, Parkinson J, Pouchkina-Stantcheva N, Riddiford N, Rosenzvit M, Salinas G, Wasmuth JD, Zamanian M, Zheng Y, Taenia solium Genome Consortium, Cai J, Soberón X, Olson PD, Laclette JP, Brehm K, Berriman M. The genomes of four tapeworm species reveal adaptations to parasitism. Nature, 2013;496(7443):57-63
|Data Source||Wellcome Sanger Institute|
This widget has been derived from the assembly-stats code developed by the Lepbase project at the University of Edinburgh