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WormBase ParaSite HomeVersion: WBPS19 (WS291)-  Archive: WBPS18

Heterobilharzia americana

BioProject PRJEB44434 | Data Source Wellcome Sanger Institute | Taxonomy ID 39320

About Heterobilharzia americana

Heterobilharzia americana (HA) is a parasitic blood fluke that infects various species of mammals, including racoons, dogs, cats, and humans. It is a trematode parasite endemic to the Gulf Coast regions of the United States which also has been reported in Kansas, North Carolina, and Indiana. The parasite's life cycle involves snails as intermediate hosts, where they release cercariae that penetrate the skin of their mammalian hosts, causing a dermatitis-like condition. Dogs are exposed to infection when immersed in freshwater lakes or streams harboring lymnaeid snails (the intermediate host). The cercariae then migrate to the lungs and liver, where they mature into adult flukes and lay eggs. Heterobilharzia americana cercariae from snails have been incriminated in causing dermatitis in humans (“swimmer’s itch”) following skin penetration.

There is 1 alternative strain from this genome project for Heterobilharzia americana available in WormBase ParaSite: tdHetHame2.1

Genome Assembly & Annotation

Assembly

This annotated genome assembly was produced as part of the doctoral thesis of Duncan Berger: [Berger, D. (2021). Comparative and population genomic analyses of the parasitic blood flukes (Doctoral thesis)](https://doi.org/10.17863/CAM.86667).

The assembly was generated from PacBio long-read sequencing data, scaffolded using and Hi-C.

The source material for genome sequencing was a single worm from USA, sample prior to 2015, and provided by Sam Loker, University of New Mexico, USA.

Annotation

Gene finding employed a customized pipeline that integrated RNA-Seq, Iso-Seq and homology data. Berger, D. (2021). Comparative and population genomic analyses of the parasitic blood flukes (Doctoral thesis).

Assembly Statistics

AssemblytdHetHame1.1, GCA_944470545.2
StraintdHetHame1.1
Database VersionWBPS19
Genome Size685,355,840
Data SourceWellcome Sanger Institute
Annotation Version2022-10-WormBase

Gene counts

Coding genes12,183
Gene transcripts16,714

Learn more about this widget in our help section

This widget has been derived from the assembly-stats code developed by the Lepbase project at the University of Edinburgh