Genome Assembly & Annotation
The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Estela Castillo (Seccion Bioquimica-Facultad de Ciencias-UDELAR- Montevideo- Uruguay) as part of the 50 Helminth Genomes project. The assembly uses Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction.
The original gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes project.
In June 2019 the predictions were improved by Alicia Costábile using MAKER and incorporating additional evidence from RNASeq data, as described in Costábile et al (2018). 8367 original genes were updated and given new identifiers, and remaining 1311 gene models from the original annotation which were no longer predicted given new evidence and methodology were preserved unchanged. The update also contains 5076 new genes not present in the original annotation.
- International Helminth Genomes Consortium. Comparative genomics of the major parasitic worms. Nat Genet, 2019;51(1):163-174
|Strain||Specht & Voge 1965|
|Data Source||Wellcome Sanger Institute|
|Non coding genes||50|
|Small non coding genes||50|
This widget has been derived from the assembly-stats code developed by the Lepbase project at the University of Edinburgh