WormBase ParaSite HomeVersion: WBPS19 (WS291)-  Archive: WBPS18

Onchocerca ochengi

BioProject PRJEB1204 | Data Source Wellcome Sanger Institute | Taxonomy ID 42157

About Onchocerca ochengi

The nematode Onchocerca ochengi is a filarial parasite of cattle, and is native to West Africa, including Cameroon. O. ochengi is very closely related to the human-parasitic Onchocerca volvulus, the tractability of the bovine host makes the O. ochengi-cattle model a useful one in vaccine and drug development work for Onchocerca.

There is 1 alternative genome project for Onchocerca ochengi available in WormBase ParaSite: PRJEB1465

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Sara Lustigman (New Yourk Blood Center) as part of the 50 Helminth Genomes project. The assembly uses Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction.

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes project. An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Key Publications

Assembly Statistics

AssemblyO_ochengi_Ngaoundere, GCA_000950515.2
StrainNgaoundere
Database VersionWBPS19
Genome Size91,660,559
Data SourceWellcome Sanger Institute
Annotation Version2016-04-WormBase

Gene counts

Coding genes12,816
Gene transcripts12,816

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