WormBase ParaSite HomeVersion: WBPS18 (WS285)-  Archive: WBPS17

Parascaris equorum

BioProject PRJEB514 | Data Source Wellcome Sanger Institute | Taxonomy ID 6256

About Parascaris equorum

The nematode Parascaris equorum, or equine roundworm, is a parasite that primarily affects young horses, usually under two years of age, as their immune response is not as developed as older horses. Can cause weight loss, ill thrift and respiratory symptoms to intussusception, intestinal impaction and death.

Genome Assembly & Annotation

Assembly

The draft genome assembly was produced by the Parasite Genomic group at the Wellcome Trust Sanger Institute, in collaboration with Jacqui Matthews (Moredun Research Institute) as part of the 50 Helminth Genomes project. The assembly uses Illumina paired-end sequencing followed by an in-house genome assembly pipeline comprising various steps, including contig assembly, scaffolding, gap-filling and error-correction.

Annotation

The gene predictions were made by the Parasite Genomics group at the Wellcome Trust Sanger Institute and WormBase, as part of the 50 Helminth Genomes project. An in-house pipeline was developed that used MAKER to generate high-quality annotations by integrating evidence from multiple sources: ab initio gene predictions from AUGUSTUS, GeneMark-ES, and SNAP; projected annotation from C. elegans (using GenBlastG) and the taxonomically nearest reference helminth genome (using RATT); and ESTs, mRNAs and proteins from related organisms aligned to the genome using BLAST, with refinement of alignments using Exonerate.

Key Publications

Assembly Statistics

AssemblyP_equorum_v1_0_4, GCA_000951375.1
Database VersionWBPS18
Genome Size185,376,996
Data SourceWellcome Sanger Institute
Annotation Version2014-06-50HGPpatch

Gene counts

Coding genes14,472
Gene transcripts14,472

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