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Schistosoma guineensis

BioProject PRJEB44434 | Data Source Wellcome Sanger Institute | Taxonomy ID 393876

About Schistosoma guineensis

Schistosoma guineensis is a parasitic flatworm that causes intestinal schistosomiasis in humans. It is endemic to West and Central Africa, with Cameroon and Equatorial Guinea having the highest prevalence of the disease. The parasite has a complex life cycle involving freshwater snails and humans, with infection occurring through contact with contaminated water.

Genome Assembly & Annotation

Assembly

This annotated genome assembly was produced as part of the doctoral thesis of Duncan Berger: [Berger, D. (2021). Comparative and population genomic analyses of the parasitic blood flukes (Doctoral thesis)](https://doi.org/10.17863/CAM.86667).

The assembly was generated from PacBio long-read sequencing data and scaffolded using Hi-C.

The source material for genome sequencing was a single adult female worm, originally obtained from São Tomé and Príncipe in 1991, archived as part of the SCAN collection at the Natural History Museum, London, and provided by Fiona Allan, Aidan Emery and Muriel Rabone. Additional worms from the same collection were used for gene finding.

Annotation

Gene finding employed a customized pipeline that integrated RNA-Seq, Iso-Seq and homology data. Berger, D. (2021). Comparative and population genomic analyses of the parasitic blood flukes (Doctoral thesis).

Assembly Statistics

AssemblytdSchGuin1.1, GCA_944470375.2
StraintdSchGuin1.1
Database VersionWBPS19
Genome Size379,339,432
Data SourceWellcome Sanger Institute
Annotation Version2022-10-WormBase

Gene counts

Coding genes9,715
Gene transcripts17,972

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