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Schistosoma mansoni

BioProject PRJEA36577 | Data Source Wellcome Trust Sanger Institute | Taxonomy ID 6183

About Schistosoma mansoni

The trematode Schistosoma mansoni is one of the three major infectious agents responsible for the chronic debilitating disease schistosomiasis found throughout Africa and South America. The intermediate host for the parasite is a freshwater snail from the genus Biomphlaria, and the definitive host is a human. Schistosomiasis is widely considered to be second only to malaria as a global health problem and an incalculable drain on the economic development of endemic countries.

Genome assembly: ASM23792v2

The S. mansoni reference genome was sequenced by a consortium led by the Wellcome Trust Sanger Institute, as described by Berriman et al (2009). The assembly version represented here is the v5.0 freeze from GeneDB (December 2013), published in Protasio et al 2012 and which corresponds with INSDC assembly ASM23792v2.

Gene annotation

The gene predictions were intially made by a consortium led by the Wellcome Trust Sanger Institute, as described by Berriman et al (2009). The gene models have since been iteratively improved, and the version represented here is the v5.0 freeze from GeneDB (December 2013) and described in Protasio et al 2012.

What can I find? Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs.

Comparative genomics

What can I find? Orthologues, paralogues, and gene trees across multiple species.

More information and statistics

Key Publications

  • Berriman M, Haas BJ, LoVerde PT, Wilson RA, Dillon GP, Cerqueira GC, Mashiyama ST, Al-Lazikani B, Andrade LF, Ashton PD, Aslett MA, Bartholomeu DC, Blandin G, Caffrey CR, Coghlan A, Coulson R, Day TA, Delcher A, DeMarco R, Djikeng A, Eyre T, Gamble JA, Ghedin E, Gu Y, Hertz-Fowler C, Hirai H, Hirai Y, Houston R, Ivens A, Johnston DA, Lacerda D, Macedo CD, McVeigh P, Ning Z, Oliveira G, Overington JP, Parkhill J, Pertea M, Pierce RJ, Protasio AV, Quail MA, Rajandream MA, Rogers J, Sajid M, Salzberg SL, Stanke M, Tivey AR, White O, Williams DL, Wortman J, Wu W, Zamanian M, Zerlotini A, Fraser-Liggett CM, Barrell BG, El-Sayed NM. The genome of the blood fluke Schistosoma mansoni. Nature, 2009;460(7253):352-358
  • Protasio AV, Tsai IJ, Babbage A, Nichol S, Hunt M, Aslett MA, De Silva N, Velarde GS, Anderson TJ, Clark RC, Davidson C, Dillon GP, Holroyd NE, LoVerde PT, Lloyd C, McQuillan J, Oliveira G, Otto TD, Parker-Manuel SJ, Quail MA, Wilson RA, Zerlotini A, Dunne DW, Berriman M. A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni. PLoS Negl Trop Dis, 2012;6(1):e1455

Statistics

AssemblyASM23792v2, GCA_000237925.2
StrainPuerto Rico
Database VersionWBPS8
Genome Size364,538,298
Data SourceWellcome Trust Sanger Institute
Annotation Version2016-05-WormBase

Gene counts

Coding genes10,772
Non coding genes1,205
Small non coding genes1,205
Pseudogenes1,336
Gene transcripts14,315

Assembly Statistics

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This widget has been derived from the assembly-stats code developed by the Lepbase project at the University of Edinburgh

About this species