About Schistosoma mansoni
The trematode Schistosoma mansoni is one of the three major infectious agents responsible for the chronic debilitating disease schistosomiasis found throughout Africa and South America. The intermediate host for the parasite is a freshwater snail from the genus Biomphlaria, and the definitive host is a human. Schistosomiasis is widely considered to be second only to malaria as a global health problem and an incalculable drain on the economic development of endemic countries.
Genome assembly: ASM23792v2
The S. mansoni reference genome was sequenced by a consortium led by the Wellcome Trust Sanger Institute, as described by Berriman et al (2009). The assembly version represented here is the v5.0 freeze from GeneDB (December 2013), published in Protasio et al 2012 and which corresponds with INSDC assembly ASM23792v2.
The gene predictions were intially made by a consortium led by the Wellcome Trust Sanger Institute, as described by Berriman et al (2009). The gene models have since been iteratively improved, and the version represented here is the v5.0 freeze from GeneDB (December 2013) and described in Protasio et al 2012.
What can I find? Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs.
What can I find? Orthologues, paralogues, and gene trees across multiple species.
- Berriman M, Haas BJ, LoVerde PT, Wilson RA, Dillon GP, Cerqueira GC, Mashiyama ST, Al-Lazikani B, Andrade LF, Ashton PD, Aslett MA, Bartholomeu DC, Blandin G, Caffrey CR, Coghlan A, Coulson R, Day TA, Delcher A, DeMarco R, Djikeng A, Eyre T, Gamble JA, Ghedin E, Gu Y, Hertz-Fowler C, Hirai H, Hirai Y, Houston R, Ivens A, Johnston DA, Lacerda D, Macedo CD, McVeigh P, Ning Z, Oliveira G, Overington JP, Parkhill J, Pertea M, Pierce RJ, Protasio AV, Quail MA, Rajandream MA, Rogers J, Sajid M, Salzberg SL, Stanke M, Tivey AR, White O, Williams DL, Wortman J, Wu W, Zamanian M, Zerlotini A, Fraser-Liggett CM, Barrell BG, El-Sayed NM. The genome of the blood fluke Schistosoma mansoni. Nature, 2009;460(7253):352-358
- Protasio AV, Tsai IJ, Babbage A, Nichol S, Hunt M, Aslett MA, De Silva N, Velarde GS, Anderson TJ, Clark RC, Davidson C, Dillon GP, Holroyd NE, LoVerde PT, Lloyd C, McQuillan J, Oliveira G, Otto TD, Parker-Manuel SJ, Quail MA, Wilson RA, Zerlotini A, Dunne DW, Berriman M. A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni. PLoS Negl Trop Dis, 2012;6(1):e1455
|Data Source||Wellcome Trust Sanger Institute|
|Non coding genes||1,205|
|Small non coding genes||1,205|