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Schistosoma haematobium

BioProject PRJNA78265 | Data Source The University of Melbourne | Taxonomy ID 6185

About Schistosoma haematobium

The trematode Schistosoma haematobium is one of the three major infectious agents responsible for the chronic debilitating disease schistosomiasis found throughout Africa and the Middle East and southern Europe. The intermediate hosts for the parasite are snails from the genus Bulinus and Physopsis and the definitive host is a human. This parasite invades the urinary system and bladder damage can lead to death.

There are 2 alternative genome projects for Schistosoma haematobium available in WormBase ParaSite: PRJEB44434 PRJEB44434

Genome Assembly & Annotation


As described by Stroehlein, et al., 2022, the S. haematobium reference genome (designated Shae.V3 – representing the Egyptian reference strain) was assembled from data produced by Oxford Nanopore long-read and Hi-C sequencing and from previous long-read and short-read data sets produced using PacBio, Illumina or Dovetail technology.


Gene models were generated using a pipeline incorporating MAKER2, EVM, and transfer from the previous "Shae.V1" gene set using liftOver and RATT. The annotation is described in full by Stroehlein et al., 2019. The gene-set presented here for the Shae. V3, was generated transferring 6277 high-confidence gene models (i.e. 67.4%) from Shae.V2 to Shae.V3, and inferred 3154 more genes based on evidence from mapped long and short RNA sequence reads from all key developmental stages and both sexes of S. haematobium, as described in full by Stroehlein et al., 2022.

Key Publications

Assembly Statistics

AssemblyUoM_Shae.V3, GCA_000699445.3
Database VersionWBPS19
Genome Size400,271,889
Data SourceThe University of Melbourne
Annotation Version2022-09-WormBase

Gene counts

Coding genes9,431
Gene transcripts14,700

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